Hey Savvy Naturalista: Cooking and Baking with Sugar Substitutes

I’m starting a new segment on the blog called Hey Savvy Naturalista, so if you have any question email me at savynaturalista@gmail.com and I will do my best to answer the question.

Hey Savvy Naturalista,
Can I use sugar free powder in any recipe, and if so will the results be the same as using regular powder sugar? Can I replace Splenda with coconut sugar?
If you would like to know the difference between coconut sugar and palm sugar, I talk a lot about it in this article: Palm Sugar